Article
Identification of Protein Vaccine Candidates from <i>Helicobacter p</i><i>ylori</i> Using a Preparative Two-Dimensional Electrophoretic Procedure and Mass Spectrometry
25 Mar 2000
Abstract excerpt
Helicobacter pylori is an important human gastric pathogen for which the entire genome sequence is known. This microorganism displays a uniquely complex pattern of binding to complex carbohydrates presented on host mucosal surfaces and other tissues, through adhesion molecules (adhesins) on the microbial cell surface. Adhesins and other membrane-associated proteins are important targets for vaccine development....
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