Three genes preceding pyrE on the Escherichia coli chromosome are essential for survival and normal cell morphology in stationary culture and at high temperature.

doi:10.1016/0923-2508(91)90042-9

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Article

Three genes preceding pyrE on the Escherichia coli chromosome are essential for survival and normal cell morphology in stationary culture and at high temperature.

Research in microbiology - 1 Jan 2000

Poulsen P, Jensen K F

Abstract excerpt

Previous studies of the upstream region of the pyrE gene in Escherichia coli revealed three genes of unknown function. Inactivation of these genes (designated orfE, orfX and orfY) by crossing the KmR-cassette-disrupted orf into the chromosome indicated that they were not required during exponenti...

Topics

Bacterial Proteins
Chromosome Mapping
Chromosomes, Bacterial
Escherichia coli
Flow Cytometry
Genes, Bacterial
Mutation
Rifampin
Sequence Homology, Nucleic Acid
Temperature

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