Article
[Genetic and epigenetic effects of lgl-tumor suppressor mutations on longevity under heat stress].
Izvestiia Akademii nauk. Seriia biologicheskaia - 1 Jan 2000
Vaĭsman N Ia, Golubovskiĭ M D
Abstract excerpt
Human populations are polymorphic for risk factor mutations predisposing to diseases and cancer. The evolutionary conservative gene, tumor suppressor lethal (2) giant larvae (lgl), whose null variants are widespread in natural Drosophila populations, can be used as a model to study this phenomeno...
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