Article
Genetics and embryological mechanisms of congenital heart diseases.
Archives of cardiovascular diseases - 1 Jan 2009
Bajolle Fanny, Zaffran Stéphane, Bonnet Damien
Abstract excerpt
Developmental genetics of congenital heart diseases has evolved from analysis of embryo sections towards molecular genetics of cardiac morphogenesis with a dynamic view of cardiac development. Lineage analysis, transgenic animal models and retrospective clonal analysis of the developing heart led to identification of different cardiac lineages and their respective roles. Genetics of congenital heart diseases has...
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