Article
Hyperserotonergic phenotype after monoamine oxidase inhibition in larval zebrafish.
Journal of neurochemistry - 1 Apr 2009
Sallinen Ville, Sundvik Maria, Reenilä Ilkka, Peitsaro Nina, Khrustalyov Denis, Anichtchik Oleg, Toleikyte Gabija, Kaslin Jan, Panula Pertti
Abstract excerpt
Serotonin (or 5-hydroxytryptamine; 5-HT) and monoamine oxidase (MAO) are involved in several physiological functions and pathological conditions. We show that the serotonergic system and its development in zebrafish are similar to those of other vertebrates rendering zebrafish a good model to study them. Development of MAO expression followed a similar time course as the 5-HT system. MAO expression and activity...
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