Article
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves.
The Journal of experimental medicine - 16 Mar 2009
Choi Jae-Hoon, Do Yoonkyung, Cheong Cheolho, Koh Hyein, Boscardin Silvia B, Oh Yong-Seok, Bozzacco Leonia, Trumpfheller Christine, Park Chae Gyu, Steinman Ralph M
Abstract excerpt
Presumptive dendritic cells (DCs) bearing the CD11c integrin and other markers have previously been identified in normal mouse and human aorta. We used CD11c promoter-enhanced yellow fluorescent protein (EYFP) transgenic mice to visualize aortic DCs and study their antigen-presenting capacity. Stellate EYFP(+) cells were readily identified in the aorta and could be double labeled with antibodies to CD11c and...
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