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Article

Mitochondrial DNA and gastrointestinal motor and sensory functions in health and functional gastrointestinal disorders.

American journal of physiology. Gastrointestinal and liver physiology - 1 Mar 2009

Camilleri Michael, Carlson Paula, Zinsmeister Alan R, McKinzie Sanna, Busciglio Irene, Burton Duane, Zaki Essam A, Boles Richard G

Abstract excerpt

Nerve, muscle, and inflammatory cells involved in gastrointestinal (GI) function have high-energy requirements and are affected in mitochondrial disorders. Familial aggregation of irritable bowel syndrome (IBS) frequently involves mothers and their children. Since mitochondrial DNA (mtDNA) is maternally inherited, mtDNA single nucleotide polymorphisms (SNPs) could confer risk to the development of IBS. The mtDNA...

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Identifiers

PMID: 19147801
DOI: 10.1152/ajpgi.90650.2008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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