Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteinase 2Apro is essential for enterovirus replication in type I interferon-treated cells.

Journal of virology - 1 May 2009

Morrison Juliet M, Racaniello Vincent R

Abstract excerpt

The Picornaviridae family comprises a diverse group of small RNA viruses that cause a variety of human and animal diseases. Some of these viruses are known to induce cleavage of components of the innate immune system and to inhibit steps in the interferon pathway that lead to the production of type I interferon. There has been no study of the effect of picornaviral infection on the events that occur after...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to Cysteine Endopeptidases
Share to Enterovirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eukaryotic Initiation Factor-4G

Share to Interferon Type I

Share to Protein Biosynthesis

Share to Viral Proteins

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 19211759
DOI: 10.1128/JVI.02177-08
PMCID: PMC2668472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteinase 2Apro is essential for enterovirus replication in type I interferon-treated cells.PMID 19211759Read ↗

Type I and Type II Interferons Inhibit the Translation of Murine Norovirus ProteinsSemantic proximity Read ↗

Innate Immune Detection of Cardioviruses and Viral Disruption of Interferon SignalingSemantic proximity Read ↗

Viral RNA at Two Stages of Reovirus Infection Is Required for the Induction of NecroptosisSemantic proximity Read ↗

An update on enterovirus 71 infection and interferon type I responseSemantic proximity Read ↗

Essential Role of Enterovirus 2A Protease in Counteracting Stress Granule Formation and the Induction of Type I InterferonSemantic proximity Read ↗

Role of Enteroviral RNA-Dependent RNA Polymerase in Regulation of MDA5-Mediated Beta Interferon ActivationSemantic proximity Read ↗

Interferon responses to norovirus infections: current and future perspectivesSemantic proximity Read ↗

Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognitionSemantic proximity Read ↗

The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferationSemantic proximity Read ↗

Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses.Semantic proximity Read ↗

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replicationSemantic proximity Read ↗

RNase L and Double-Stranded RNA-Dependent Protein Kinase Exert Complementary Roles in Islet Cell Defense during Coxsackievirus InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.