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Article

A novel diagnostic target in the hepatitis C virus genome.

PLoS medicine - 10 Feb 2009

Drexler Jan Felix, Kupfer Bernd, Petersen Nadine, Grotto Rejane Maria Tommasini, Rodrigues Silvia Maria Corvino, Grywna Klaus, Panning Marcus, Annan Augustina, Silva Giovanni Faria, Douglas Jill, Koay Evelyn S C, Smuts Heidi, Netto Eduardo M, Simmonds Peter, Pardini Maria Inês de Moura Campos, Roth W Kurt, Drosten Christian

Abstract excerpt

BACKGROUND: Detection and quantification of hepatitis C virus (HCV) RNA is integral to diagnostic and therapeutic regimens. All molecular assays target the viral 5'-noncoding region (5'-NCR), and all show genotype-dependent variation of sensitivities and viral load results. Non-western HCV genoty...

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Identifiers

PMID: 19209955
DOI: 10.1371/journal.pmed.1000031
PMCID: PMC2637920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19209955-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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