Article
Prohibitin is overexpressed in papillary thyroid carcinomas bearing the BRAF(V600E) mutation.
Thyroid : official journal of the American Thyroid Association - 1 Mar 2009
Franzoni Alessandra, Dima Mariavittoria, D'Agostino Maria, Puppin Cinzia, Fabbro Dora, Loreto Carla Di, Pandolfi Maura, Puxeddu Efisio, Moretti Sonia, Celano Marilena, Bruno Rocco, Filetti Sebastiano, Russo Diego, Damante Giuseppe
Abstract excerpt
BACKGROUND: Prohibitin (PHB) is a multifunctional protein that is localized in different intracellular sites. PHB may exert different roles in tumorigenesis, having either a permissive action on tumor growth or an oncosuppressor role, depending on the cellular context. The objective of this study...
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