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Article

Is genetic evolution predictable?

Science (New York, N.Y.) - 6 Feb 2009

Stern David L, Orgogozo Virginie

Abstract excerpt

Ever since the integration of Mendelian genetics into evolutionary biology in the early 20th century, evolutionary geneticists have for the most part treated genes and mutations as generic entities. However, recent observations indicate that all genes are not equal in the eyes of evolution. Evolutionarily relevant mutations tend to accumulate in hotspot genes and at specific positions within genes. Genetic...

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Identifiers

PMID: 19197055
DOI: 10.1126/science.1158997
PMCID: PMC3184636

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