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Article

Clinical heterogeneity of duchenne muscular dystrophy (DMD): definition of sub-phenotypes and predictive criteria by long-term follow-up.

PloS one - 1 Jan 2009

Desguerre Isabelle, Christov Christo, Mayer Michele, Zeller Reinhard, Becane Henri-Marc, Bastuji-Garin Sylvie, Leturcq France, Chiron Catherine, Chelly Jamel, Gherardi Romain K

Abstract excerpt

BACKGROUND: To explore clinical heterogeneity of Duchenne muscular dystrophy (DMD), viewed as a major obstacle to the interpretation of therapeutic trials METHODOLOGY/PRINCIPAL FINDINGS: A retrospective single institution long-term follow-up study was carried out in DMD patients with both complete lack of muscle dystrophin and genotyping. An exploratory series (series 1) was used to assess phenotypic...

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Source

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Identifiers

PMID: 19194511
DOI: 10.1371/journal.pone.0004347
PMCID: PMC2633042

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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