Article
Visualization of a missing link in retrovirus capsid assembly.
Nature - 5 Feb 2009
Cardone Giovanni, Purdy John G, Cheng Naiqian, Craven Rebecca C, Steven Alasdair C
Abstract excerpt
For a retrovirus such as HIV to be infectious, a properly formed capsid is needed; however, unusually among viruses, retrovirus capsids are highly variable in structure. According to the fullerene conjecture, they are composed of hexamers and pentamers of capsid protein (CA), with the shape of a capsid varying according to how the twelve pentamers are distributed and its size depending on the number of hexamers....
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