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Article

Survival-Related Profile, Pathways, and Transcription Factors in Ovarian Cancer

30 Jan 2009

Abstract excerpt

BACKGROUND: Ovarian cancer has a poor prognosis due to advanced stage at presentation and either intrinsic or acquired resistance to classic cytotoxic drugs such as platinum and taxoids. Recent large clinical trials with different combinations and sequences of classic cytotoxic drugs indicate that further significant improvement in prognosis by this type of drugs is not to be expected. Currently a large number of...

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PMID: 19192944
DOI: 10.1371/journal.pmed.1000024

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