Article
Prenatal stress or high-fat diet increases susceptibility to diet-induced obesity in rat offspring.
Diabetes - 1 May 2009
Tamashiro Kellie L K, Terrillion Chantelle E, Hyun Jayson, Koenig James I, Moran Timothy H
Abstract excerpt
OBJECTIVE: Perturbations to the prenatal environment have been associated with the development of adult chronic disease, findings that gave rise to the "Barker Hypothesis" or the "developmental origins of adult disease" concept. In this study, we used an animal model to determine the metabolic consequences of maternal prenatal stress and high-fat feeding on the developing offspring. RESEARCH DESIGN AND METHODS:...
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