Article
Clinical utility of array comparative genomic hybridization: uncovering tumor susceptibility in individuals with developmental delay.
The Journal of pediatrics - 1 Jan 2009
Adam Margaret P, Justice April N, Schelley Susan, Kwan Andrea, Hudgins Louanne, Martin Christa L
Abstract excerpt
Microarray-based comparative genomic hybridization can determine genome-wide copy number alterations at the kilobase level. We highlight the clinical utility of microarray-based comparative genomic hybridization in determining tumor susceptibility in 3 patients with dysmorphic features and developmental delay, likely decreasing both morbidity and mortality in these patients.
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