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Interpretation of Array Comparative Genome Hybridization Data: A Major Challenge

1 Jan 2011

Abstract excerpt

The advent and application of high-resolution array-based comparative genome hybridization (array CGH) has led to the detection of large numbers of copy number variants (CNVs) in patients with developmental delay and/or multiple congenital anomalies as well as in healthy individuals. The notion that CNVs are also abundantly present in the normal population challenges the interpretation of the clinical...

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PMID: 22086107
DOI: 10.1159/000334066

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