Article
HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power--an intermediate phenotype for alcoholism and co-morbid behaviors.
Alcohol (Fayetteville, N.Y.) - 1 Feb 2009
Ducci Francesca, Enoch Mary-Anne, Yuan Qiaoping, Shen Pei-Hong, White Kenneth V, Hodgkinson Colin, Albaugh Bernard, Virkkunen Matti, Goldman David
Abstract excerpt
Alcohol use disorders (AUD) with co-morbid antisocial personality disorder (ASPD) have been associated with serotonin (5-HT) dysfunction. 5-HT3 receptors are potentiated by ethanol and appear to modulate reward. 5-HT3 receptor antagonists may be useful in the treatment of early-onset alcoholics with co-morbid ASPD. Low-voltage alpha electroencephalogram (EEG) power, a highly heritable trait, has been associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
