Article
Discrimination of a transformation phenotype in Syrian golden hamster embryo (SHE) cells using ATR-FTIR spectroscopy.
Toxicology - 5 Apr 2009
Walsh Michael J, Bruce Shannon W, Pant Kamala, Carmichael Paul L, Scott Andrew D, Martin Francis L
Abstract excerpt
Primary Syrian hamster embryo (SHE) cells might be used to assess morphological transformation following treatment with chemical carcinogens. We employed attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy to interrogate SHE colonies, as complex biomolecules absorb in the mid-infrared (IR; lambda=2-20microm) giving vibrational spectra associated with structure and function....
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