Article
Flies as the ointment: Drosophila modeling to enhance drug discovery.
Fly - 1 Jan 2000
Bell Aaron J, McBride Sean M J, Dockendorff Thomas C
Abstract excerpt
Development of a drug and its safe therapeutic application necessitates using animal models for testing purposes. While testing with mammalian models is essential prior to approval for human trials, the use of invertebrate animal models that are amenable to molecular genetic manipulations provide experimental and biological advantages that can streamline the discovery and testing process. Among the benefits of a...
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