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Article

[Survey of the evolutionary characteristics of influenza H1N1 hemagglutinin gene HA1 in 2000-2009].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jan 2010

Wang Ni-sha, Ma Wen-li, Zhao Hai-quan, Wei Min, Zhang Bao, Zhang Wen-ling, Xiang Xing-yu

Abstract excerpt

OBJECTIVE: To study the global evolutionary characteristics of hemagglutinin gene HA1 of influenza H1N1 infecting different species during 2000-2009. METHODS: The target sequences were downloaded from NCBI and analyzed using bioinformatic software to construct the phylogenetic tree. RESULTS: The HA1 amino acid sequences of influenza H1N1 contained four mutated antigenic sites and receptor-binding sites, and the...

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PMID: 20117993

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