Article
Pediatric sinonasal neuroendocrine carcinoma after treatment of retinoblastoma.
Human pathology - 1 May 2009
Franchi Alessandro, Sardi Iacopo, Cetica Valentina, Buccoliero Annamaria, Giordano Flavio, Mussa Federico, Genitori Lorenzo, Oliveri Giuseppe, Miracco Clelia
Abstract excerpt
Patients who survive retinoblastoma are at risk for developing additional malignant neoplasms, including tumors of the sinonasal tract. We report 2 cases of secondary sinonasal malignancy arising in pediatric patients previously treated for retinoblastoma, with features of neuroendocrine carcinoma. Both lesions were characterized by a proliferation of round to oval cells arranged in solid sheets, trabeculae, and...
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