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Article

Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling

24 Dec 2008

Abstract excerpt

In an attempt to identify potential therapeutic targets for the correction of muscle wasting, the gene expression of several pivotal proteins involved in protein metabolism was investigated in experimental atrophy induced by transient or definitive denervation, as well as in four animal models of muscular dystrophies (deficient for calpain 3, dysferlin, alpha-sarcoglycan and dystrophin, respectively). The results...

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PMID: 19143834
DOI: 10.1111/j.1742-4658.2008.06814.x

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