Article
Copy number variation showers in schizophrenia: an emerging hypothesis.
Molecular psychiatry - 1 Apr 2009
Singh S M, Castellani C A, O'Reilly R L
Abstract excerpt
Genetic discoveries on Schizophrenia remain challenging. Traditional approaches have provided clues, but no genes. Novel theories that must account for extensive heterogeneity, including high discordance of monozygotic (MZD) twins, are needed. To this end, the extensive repeats of the human genome may provide the predisposition for DNA replication errors operational at every cell cycle during meiosis and mitosis....
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