Article
DNA testing for live kidney donors at risk for autosomal dominant polycystic kidney disease.
Transplantation - 15 Jan 2009
Huang Edmund, Samaniego-Picota Millie, McCune Thomas, Melancon Joseph K, Montgomery Robert A, Ugarte Richard, Kraus Edward, Womer Karl, Rabb Hamid, Watnick Terry
Abstract excerpt
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by age-dependent growth of kidney cysts with end-stage renal disease developing in approximately 50% of affected individuals. Living donors from ADPKD families are at risk for developing ADPKD and may be excluded from renal donation if the diagnosis cannot be conclusively ruled out. Radiographic imaging may be adequate to screen for kidney...
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