Article
Interaction between variant apolipoproteins C-II and E that affects plasma lipoprotein concentrations.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000
Hegele R A, Breckenridge W C, Cox D W, Maguire G F, Little J A, Connelly P W
Abstract excerpt
The genes for apolipoprotein (apo) C-II, a cofactor for activation of lipoprotein lipase, and apo E, a ligand for receptor-mediated uptake of triglyceride-rich lipoproteins, are physically linked on chromosome 19q13.1. In a large Caribbean Caucasian family, several individuals had clinical featur...
Topics
- Adult
- Aged
- Apolipoprotein C-II
- Apolipoproteins C
- Apolipoproteins E
- Cholesterol, HDL
- Cholesterol, VLDL
- Chromosome Deletion
- Chromosomes, Human, Pair 19
- Female
- Genetic Linkage
- Heterozygote
- Humans
- Hyperlipoproteinemia Type V
- Male
- Middle Aged
- Phenotype
- Triglycerides