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Article

GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability.

Expert review of neurotherapeutics - 1 Jan 2009

Costa Erminio, Chen Ying, Dong Erbo, Grayson Dennis R, Kundakovic Marija, Maloku Ekrem, Ruzicka William, Satta Rosalba, Veldic Marin, Zhubi Adrian, Guidotti Alessandro

Abstract excerpt

The neuronal GABAergic mechanisms that mediate the symptomatic beneficial effects elicited by a combination of antipsychotics with valproate (a histone deacetylase inhibitor) in the treatment of psychosis (expressed by schizophrenia or bipolar disorder patients) are unknown. This prompted us to investigate whether the beneficial action of this combination results from a modification of histone tail covalent...

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Source

Identifiers

PMID: 19102671
DOI: 10.1586/14737175.9.1.87

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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