Biomaterial-induced sarcomagenesis is not associated with microsatellite instability.

doi:10.1007/s00428-008-0705-7

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Article

Biomaterial-induced sarcomagenesis is not associated with microsatellite instability.

Virchows Archiv : an international journal of pathology - 1 Feb 2009

Weber Achim, Strehl Annette, Springer Erik, Hansen Torsten, Schad Arno, Kirkpatrick C James

Abstract excerpt

Sarcomagenesis, in contrast to carcinogenesis, is poorly understood. Microsatellite instability has been implicated in the development of many cancers, in particular those associated with chronic inflammatory conditions. In an experimental animal model, rats developed not only a peri-implantation...

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