Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.

doi:10.1155/2008/426764

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Article

Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.

Disease markers - 1 Jan 2008

Kitahara Kei, Kawa Shigeyuki, Katsuyama Yoshihiko, Umemura Takeji, Ozaki Yayoi, Takayama Mari, Arakura Norikazu, Ota Masao

Abstract excerpt

Alcohol abuse is one of the most common risk factor for chronic pancreatitis, but the underlying pathophysiological mechanisms remain unclear. The aim of this study was to identify genes that contribute to susceptibility or resistance for alcoholic chronic pancreatitis by screening the whole genome. Sixty-five patients with alcoholic chronic pancreatitis (63 men and 2 women, mean age 55.2 years) and 99 healthy...

Read the complete abstract on PubMed