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Development and evaluation of a real-time one step Reverse-Transcriptase PCR for quantitation of Chandipura Virus

1 Dec 2008

Abstract excerpt

BACKGROUND: Chandipura virus (CHPV), a member of family Rhabdoviridae was attributed to an explosive outbreak of acute encephalitis in children in Andhra Pradesh, India in 2003 and a small outbreak among tribal children from Gujarat, Western India in 2004. The case-fatality rate ranged from 55-75%. Considering the rapid progression of the disease and high mortality, a highly sensitive method for quantifying CHPV...

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PMID: 19091082
DOI: 10.1186/1471-2334-8-168

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