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Article

[Prediction and immunologic identification of antigenic epitopes in genus-specific outer membrane protein LipL41 of Leptospira interrogans].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 Nov 2008

Jiang Jiu-kun, Lin Xu-ai, Yan Jie

Abstract excerpt

OBJECTIVE: To predict and screen the efficient antigenic epitopes in genus-specific envelope protein LipL41 of Leptospira interrogans and to determine the immunoreactive diversity of LipL41s from different genotypes. METHODS: Bioinformatic methods were applied to predict the T/B combined epitope candidates in LipL41/1 and LipL41/2 molecules. The nucleotide fragments encoding epitopes were amplified by PCR. Phage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19084956
DOI: 10.3785/j.issn.1008-9292.2008.06.008

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