Article
Resolving relationship tests that show ambiguous STR results using autosomal SNPs as supplementary markers.
Forensic science international. Genetics - 1 Jun 2008
Phillips C, Fondevila M, García-Magariños M, Rodriguez A, Salas A, Carracedo A, Lareu M V
Abstract excerpt
When using a standard battery of STRs for relationship testing a small proportion of analyses can give ambiguous results - where the claimed relationship cannot be confirmed by a high enough paternity index or excluded with fully incompatible genotypes. The majority of such cases arise from unknowingly testing a brother of the true father and observing only a small number of exclusions that can each be...
Topics
- Alleles
- Computer Simulation
- DNA Fingerprinting
- Fathers
- Forensic Medicine
- Gene Frequency
- Genetic Markers
- Genotype
- Humans
- Likelihood Functions
- Microsatellite Repeats
- Mutation
- Paternity
- Pedigree
- Polymorphism, Single Nucleotide