Comparative evaluation of alternative batteries of genetic markers to complement autosomal STRs in kinship investigations: autosomal indels vs. X-chromosome STRs.

Abstract excerpt

Kinship investigations such as paternity are currently solved using sets of (commercially available) highly polymorphic autosomal short tandem repeats (STRs), which lead to powerful likelihood ratios (LR). Still, some difficult cases arise whenever the kinship is much more remote or if the alternative hypotheses are not correctly formulated due to the lack of information (for e.g. there is an unknown relationship...

Topics

• Alleles
• Chromosomes, Human, X
• Female
• Forensic Genetics
• Genetic Markers
• Genotype
• Humans
• INDEL Mutation
• Likelihood Functions
• Male
• Mendelian Randomization Analysis
• Microsatellite Repeats
• Paternity