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Article

Inferring ancestral origin using a single multiplex assay of ancestry-informative marker SNPs.

Forensic science international. Genetics - 1 Dec 2007

Phillips C, Salas A, Sánchez J J, Fondevila M, Gómez-Tato A, Alvarez-Dios J, Calaza M, de Cal M Casares, Ballard D, Lareu M V, Carracedo A

Abstract excerpt

Tests that infer the ancestral origin of a DNA sample have considerable potential in the development of forensic tools that can help to guide crime investigation. We have developed a single-tube 34-plex SNP assay for the assignment of ancestral origin by choosing ancestry-informative markers (AIMs) exhibiting highly contrasting allele frequency distributions between the three major population-groups. To predict...

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PMID: 19083773
DOI: 10.1016/j.fsigen.2007.06.008

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