Article
Developmental validation of mitochondrial DNA genotyping assays for adept matrilineal inference of biogeographic ancestry at a continental level.
Forensic science international. Genetics - 1 Jul 2014
Chaitanya Lakshmi, van Oven Mannis, Weiler Natalie, Harteveld Joyce, Wirken Laura, Sijen Titia, de Knijff Peter, Kayser Manfred
Abstract excerpt
Mitochondrial DNA (mtDNA) can be used for matrilineal biogeographic ancestry prediction and can thus provide investigative leads towards identifying unknown suspects, when conventional autosomal short tandem repeat (STR) profiling fails to provide a match. Recently, six multiplex genotyping assays targeting 62 ancestry-informative mitochondrial single nucleotide polymorphisms (mt-SNPs) were developed. This...
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