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Article

A single-tube 27-plex SNP assay for estimating individual ancestry and admixture from three continents.

International journal of legal medicine - 1 Jan 2016

Wei Yi-Liang, Wei Li, Zhao Lei, Sun Qi-Fan, Jiang Li, Zhang Tao, Liu Hai-Bo, Chen Jian-Gang, Ye Jian, Hu Lan, Li Cai-Xia

Abstract excerpt

A single-tube multiplex assay of a small set of ancestry-informative markers (AIMs) for effectively estimating individual ancestry and admixture is an ideal forensic tool to trace the population origin of an unknown DNA sample. We present a newly developed 27-plex single nucleotide polymorphism (SNP) panel with highly robust and balanced differential power to perfectly assign individuals to African, European, and...

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PMID: 25833170
DOI: 10.1007/s00414-015-1183-5

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