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Article

Forensic STRs as potential disease markers: a study of VWA and von Willebrand's Disease.

Forensic science international. Genetics - 1 Dec 2007

Laird Rebecca, Schneider Peter M, Gaudieri Silvana

Abstract excerpt

In recent years it has been established that non-coding variants may be in linkage disequilibrium (LD) with coding variants up to several thousand base pairs away forming haplotype blocks. These non-coding markers may be haplotype specific and, therefore, informative regarding the surrounding coding sequence. In this study, we chose to study the VWA short tandem repeat (STR) as it is targeted in all major...

Topics

Alleles
DNA Fingerprinting
Female
Forensic Genetics
Gene Frequency
Genetic Markers
Haplotypes
Humans
Linkage Disequilibrium
Male
Microsatellite Repeats
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Taiwan

von Willebrand Diseases

von Willebrand Factor

Source

Identifiers

PMID: 19083770
DOI: 10.1016/j.fsigen.2007.06.002

Provenance

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