Article
A preliminary study of genetic diversity of MSP-1 types in Plasmodium falciparum in southern province of Sistan Baluchistan of Iran.
Pakistan journal of biological sciences : PJBS - 1 Feb 2007
Zahra Zamani, Reza Razavi Mohammad, Mehdi Assmar, Sedigheh Sadeghi, Fatemeh Pourfallah, Nikoo Nasoohi, Ashraf Sheibani, Mohammad Raisi
Abstract excerpt
Plasmodiumfalciparum merozoite surface protein-1 (MSP-1) shows extensive antigenic diversity. This is due to the presence of seven variable blocks, five semi-conserved and also five conserved blocks. The variable blocks in the MSP-1 gene are principally dimorphic, displaying either K1 or MAD20 type; except for the block 2 region which is represented by three alleles, an RO33 type in addition to the other two....
Topics
- Alleles
- Animals
- Genetic Variation
- Genotype
- Humans
- Iran
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Plasmodium falciparum