Article
[Genetic dissection of intracranial aneurysm].
Brain and nerve = Shinkei kenkyu no shinpo - 1 Nov 2008
Onda Hideaki, Yoneyama Taku, Akagawa Hiroyuki, Kasuya Hidetoshi
Abstract excerpt
Subarachnoid hemorrhage (SAH) due to rupture of an intracranial aneurysm (IA) is a devastating condition with high mortality and morbidity. Genetic as well as environment factors play important roles in the pathogenesis of SAH and IAs. We review the present knowledge on the genetic factors responsible for SAH or IAs. Linkage analysis and association study are used for genetic dissection. Genome-wide linkage...
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