Article
How different are luminal A and basal breast cancers?
International journal of cancer - 15 Mar 2009
Bertucci François, Finetti Pascal, Cervera Nathalie, Charafe-Jauffret Emmanuelle, Buttarelli Max, Jacquemier Jocelyne, Chaffanet Max, Maraninchi Dominique, Viens Patrice, Birnbaum Daniel
Abstract excerpt
Heterogeneity of breast cancer makes its evolution difficult to predict, and its treatment far from being optimal. At least 5 main molecular subtypes exist. Two major subtypes are luminal A and basal subtypes, which have opposite features, notably survival. To characterize these 2 subtypes better, with the hope of better understanding their different biology and clinical outcome, we have profiled a series of 138...
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