Article
Comparison of arachidonate metabolism by alveolar macrophages from bighorn and domestic sheep.
Inflammation - 1 Feb 1991
Silflow R M, Foreyt W J, Taylor S M, Laegreid W W, Liggitt H D, Leid R W
Abstract excerpt
We have defined the metabolites of arachidonic acid (AA) secreted by alveolar macrophages (AMs) of bighorn sheep and domestic sheep in response to three agents: calcium ionophore A23187, phorbol myristate acetate (PMA), and opsonized zymosan. Cells were labeled with [3H]AA prior to stimulation an...
Topics
- Animals
- Arachidonic Acid
- Arachidonic Acids
- Calcimycin
- Cells, Cultured
- Disease Susceptibility
- Female
- Genetic Predisposition to Disease
- Lipoxygenase
- Macrophages
- Male
- Prostaglandin-Endoperoxide Synthases
- Pulmonary Alveoli
- Respiratory Tract Infections
- Sheep
- Species Specificity
- Tetradecanoylphorbol Acetate
- Zymosan