Article
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions.
BMC bioinformatics - 1 Dec 2008
Su Shu-Yi, White Jonathan, Balding David J, Coin Lachlan J M
Abstract excerpt
BACKGROUND: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organisms. For polyploids, however, the difficulty of determining phase has limited such approaches. Polyploidy is common i...
Topics
- Chromosomes, Human, X
- Computer Simulation
- Gene Dosage
- Genetic Variation
- Genetics, Population
- Genome, Human
- Genotype
- Haplotypes
- Humans
- Male
- Polymorphism, Single Nucleotide
- Polyploidy
- Software