Article
Prevalence of Helicobacter pylori pathogenicity-associated cagA and vacA genotypes among Pakistani dyspeptic patients.
FEMS immunology and medical microbiology - 1 Jan 2009
Ahmad Tanvir, Sohail Khawar, Rizwan Muhammad, Mukhtar Muhammad, Bilal Rakhshanda, Khanum Azra
Abstract excerpt
The cytotoxin-associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA) products are considered the most important pathogenic determinants of Helicobacter pylori, a gram-negative bacterium causing gastrointestinal disorders such as duodenal ulcers, gastritis and mucosa-associated lymphoid tissue disease. A higher prevalence of H. pylori has been reported in various regions in the Pakistani population;...
Topics
- Adult
- Aged
- Antigens, Bacterial
- Bacterial Proteins
- Biopsy
- DNA, Bacterial
- Female
- Gastric Mucosa
- Genotype
- Helicobacter Infections
- Helicobacter pylori