Article
Blood group ABO antigen expression in human embryonic stem cells and in differentiated hepatocyte- and cardiomyocyte-like cells.
Transplantation - 27 Nov 2008
Mölne Johan, Björquist Petter, Andersson Katarina, Diswall Mette, Jeppsson Anders, Strokan Valeri, Rydberg Lennart, Breimer Michael E
Abstract excerpt
BACKGROUND: The use of stem cells in regenerative medicine and transplantation may require grafting of cells that will challenge the recipient's immune system. Our knowledge of tissue antigen expression in human embryonic stem cells (hESC) and during their differentiation is limited, especially regarding histo-blood group AB(O)H antigens. METHODS: Nine different hESC lines, and hESC-derived hepatocyte- and...
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