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Article

Acquired resistance to interferon alpha therapy associated with homozygous MPL-W515L mutation and chromosome 20q deletion in primary myelofibrosis.

European journal of haematology - 1 Feb 2009

Buxhofer-Ausch Veronika, Gisslinger Heinz, Berg Tiina, Gisslinger Bettina, Kralovics Robert

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Topics

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 20
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MPL gene

Share to Homozygote

Share to Interferon-alpha

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Source

Identifiers

PMID: 19018861
DOI: 10.1111/j.1600-0609.2008.01183.x

Genes

MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 11 closest

Acquired resistance to interferon alpha therapy associated with homozygous MPL-W515L mutation and chromosome 20q deletion in primary myelofibrosis.PMID 19018861Read ↗

Essential thrombocythemia with MPL W515S mutation.Semantic proximity Read ↗

Identification of MPL W515L/K mutations in patients with primary myelofibrosis and essential thrombocythaemia by allele-specific polymerase chain reaction.Semantic proximity Read ↗

Interferon-alpha may restore sensitivity to tyrosine-kinase inhibitors in Philadelphia chromosome positive acute lymphoblastic leukaemia with F317L mutation.Semantic proximity Read ↗

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Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCTSemantic proximity Read ↗

Interferon-α Based Individualized Treatment of a High Risk Chronic Myelogenous Leukemia Patient Harboring T315I Mutation.Semantic proximity Read ↗

Detection of an MPLW515 mutation in a case with features of both essential thrombocythemia and refractory anemia with ringed sideroblasts and thrombocytosis.Semantic proximity Read ↗

The effectiveness of interferon-α combined with imatinib in patient with chronic myeloid leukemia harboring T315I BCR-ABL1 mutation.Semantic proximity Read ↗

Interferon-alpha or homoharringtonine as salvage treatment for chronic myeloid leukemia patients who acquire the T315I BCR-ABL mutation.Semantic proximity Read ↗

Is there a role for the use of IFN-α in primary myelofibrosis?Semantic proximity Read ↗

Resistance to therapy in acute promyelocytic leukemia.Semantic proximity Read ↗

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