Race does not explain genetic heterogeneity in pharmacogenomic pathways.

Abstract excerpt

INTRODUCTION: Polymorphic alleles in the human genome have been identified as affecting numerous drug responses. Currently, genotyping of all patients before starting a drug regimen is impractical. Since many polymorphisms occur at varying rates in different racial groups, we investigated whether a patient's race could predict presence of drug-relevant genetic variants well enough to be used as a substitute for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Camptothecin
• Share to Fluorouracil
• Share to Genetic Heterogeneity