Article
Response to neo-adjuvant chemotherapy in BRCA1 and BRCA2 related stage III breast cancer.
Familial cancer - 1 Jan 2009
Hubert Ayala, Mali Bela, Hamburger Tamar, Rottenberg Yakir, Uziely Beatrice, Peretz Tamar, Kadouri Luna
Abstract excerpt
Pathological features and consequently, tumor response differ between BRCA1/2 carriers and sporadic breast cancer (BC) cases. It is expected that BRCA1/2 associated tumors will be more vulnerable to DNA damaging agents and irradiation due to their function in DNA repair. In addition, very high pa...
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