Article
Molecular evolution of hemagglutinin genes of H1N1 swine and human influenza A viruses.
Journal of molecular evolution - 1 Jan 1991
Sugita S, Yoshioka Y, Itamura S, Kanegae Y, Oguchi K, Gojobori T, Nerome K, Oya A
Abstract excerpt
The hemagglutinin (HA) genes of influenza type A (H1N1) viruses isolated from swine were cloned into plasmid vectors and their nucleotide sequences were determined. A phylogenetic tree for the HA genes of swine and human influenza viruses was constructed by the neighbor-joining method. It showed that the divergence between swine and human HA genes might have occurred around 1905. The estimated rates of synonymous...
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