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Article

Structural and functional properties of reconstituted high density lipoprotein discs prepared with six apolipoprotein A-I variants.

Journal of lipid research - 1 Jan 1991

Jonas A, von Eckardstein A, Kézdy K E, Steinmetz A, Assmann G

Abstract excerpt

Six apolipoprotein A-I (apoA-I) variants containing the following amino acid changes: Pro3----Arg, Pro4----Arg, Lys107----0 (Lys deletion) Lys107----Met, Pro165----Arg, and Glu198----Lys, and the corresponding normal allele products, were isolated by preparative isoelectric focusing from heterozygous individuals. The apoA-I samples were reconstituted with palmitoyloleoyl phosphatidylcholine (POPC) or dipalmitoyl...

Topics

Amino Acid Sequence
Apolipoprotein A-I
Apolipoproteins A
Densitometry
Fluorescence
Genetic Variation
Humans
Isoelectric Focusing
Kinetics
Lipoproteins, HDL
Particle Size

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphatidylcholine-Sterol O-Acyltransferase

Structure-Activity Relationship

Temperature

Source

Identifiers

PMID: 1901346

Genes

LCAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1901346-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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