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Article

Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2009

Laé Marick, Fréneaux Paul, Sastre-Garau Xavier, Chouchane Olfa, Sigal-Zafrani Brigitte, Vincent-Salomon Anne

Abstract excerpt

Secretory breast carcinomas (<0.15% of breast tumors) are associated with a characteristic morphology and a favorable prognosis. Remarkably, this entity is the only epithelial tumor of the breast with a balanced translocation, t(12;15), that creates an ETV6-NTRK3 gene fusion encoding chimeric tyrosine kinase also encountered in cellular mesoblastic nephroma and infantile fibrosarcoma. The aim of this study was to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Share to Oncogene Proteins, Fusion

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Source

Identifiers

PMID: 19011601
DOI: 10.1038/modpathol.2008.184

Genes

ETV6
ERBB2
NTRK3
EGFR
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum.PMID 19011601Read ↗

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