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Article

Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2009

Laé Marick, Fréneaux Paul, Sastre-Garau Xavier, Chouchane Olfa, Sigal-Zafrani Brigitte, Vincent-Salomon Anne

Abstract excerpt

Secretory breast carcinomas (<0.15% of breast tumors) are associated with a characteristic morphology and a favorable prognosis. Remarkably, this entity is the only epithelial tumor of the breast with a balanced translocation, t(12;15), that creates an ETV6-NTRK3 gene fusion encoding chimeric tyr...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Immunophenotyping

Share to In Situ Hybridization, Fluorescence

Share to Neoplasm Invasiveness

Share to Oncogene Proteins, Fusion

Share to Translocation, Genetic

Source

Identifiers

PMID: 19011601
DOI: 10.1038/modpathol.2008.184

Genes

ETV6
ERBB2
NTRK3
EGFR
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19011601-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Secretory breast carcinomas with ETV6-NTRK3 fusion gene belong to the basal-like carcinoma spectrum.PMID 19011601Read ↗

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